Pros
Quiet, generally laid back, decent benefits, nice people. Great location in Olde City.
Cons
Management varies widely from department to department. Some managers are not very well qualified. Managers are heard to say some things that would get you fired anywhere else. Bad situations are left to go on much too long. Workers are generally dissatisfied. If the market were better, most people would quit. Management thinks we are all fascinated with cancer research, but we're not, we just need a job. Don't have off on most federal holidays. Sometimes we are the only ones working in the building (or in the city, for that matter). Rarely closes for snow, even when dangerous. Harassed about lateness constantly, even if it's only 5 minutes. No working from home option. No flextime. No hire back policy. It used to be much nicer but it's getting bigger and crappier every day.