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Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

Senior Staff Software Program Manager, NPI (NGS)

Illumina is seeking a Senior Staff Software Program Manager to lead the software program for a new sequencing instrument. This role focuses on driving software development activities across the New Product Introduction (NPI) development cycle - from concept and architecture through verification, validation, launch, and transition to on‑market support.

The ideal candidate brings strong experience in software development lifecycles (SDLC) and product development processes (PDP), along with a background in instrumentation, embedded systems, and regulated product development. Familiarity with various sequencing technologies and medical device design controls is highly preferred.

Responsibilities:

• Leading Instrument Software Workstreams throughout the NPI lifecycle, developing executable project plans, defining scope & goals, establishing WBS, and driving task ownership across engineering teams.
• Develop and manage detailed software schedules, resource plans, dependencies, and critical path analyses to ensure program milestones are achieved.
• Drive system‑level integration planning for firmware, control software, data pipelines, cloud services, and user interfaces.
• Form and lead cross‑functional software extended teams, including by not limited to technical product management, system engineering, embedded systems, cloud, and test engineering.
• Identify program risks early and implement mitigation strategies; develop and track software KPIs and health indicators.
• Partner closely with Systems, Hardware, and Advanced Science teams to ensure alignment between workflows and instrument software design.
• Deliver regular updates to senior leadership on progress, risks, and cross‑functional alignment throughout the NPI phase.

• Work with software development, DevOps, software quality and support teams to deliver and ensure timely all software deliverables.
• Champion continuous improvement initiatives in software processes, tooling, and execution discipline across the NPI portfolio.

Requirements:

• Proven experience in product development lifecycle and NPI program management.
• Experience managing software development projects including SW releases, environment management, and embedded FW/SW development.
• Strong working knowledge of SCRUM, SAFe, Kanban, waterfall, or hybrid models.
• Advanced proficiency with Smartsheet, Office Timeline, Jira, and Confluence.
• Experience in regulated industry with understanding of design controls (21 CFR 820.30, ISO 13485:2016, ISO 14971:2019, IEC 62304:2006).
• Familiarity with NGS workflows, data analysis, and sequencing instrumentation.

Education and Experience:

• Bachelor’s or Master’s Degree (Computer Science/Engineering, Software/Electrical Engineering), with at least 15 years of MNC working experience in a regulated industry on product development (preferably on Medical Devices).
• More than 10 years as a software project manager
PMP certification will be a plus.

We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. Illumina conducts background checks on applicants for whom a conditional offer of employment has been made. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable local, state, and federal laws. Background check results may potentially result in the withdrawal of a conditional offer of employment. The background check process and any decisions made as a result shall be made in accordance with all applicable local, state, and federal laws. Illumina prohibits the use of generative artificial intelligence (AI) in the application and interview process. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf. The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants. This role is not eligible for visa sponsorship.